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ICTS Mentored Research Fellowship and Training Programs


"Building the next generation of clinician researchers translational science scholars - a unique opportunity for physicians, health scientists, and translational basic science investigators early in their careers."


The ICTS offeres funding for 3 Menotred KL-2 Fellowship positions and 10 Pre and Post Doctoral TL-1 Scholar Trainees.

KL-2 Career Development Award Information »



Currently there are no available positions


The UC Irvine Institute for Clinical and Translational Science (ICTS) proudly announces a new call for the NIH/NCATS Mentored Career award (KL-2) under the UCI Clinical and Translational Science Award (CTSA/ICTS). The ICTS-KL-2 award is intended to support a two-year period of mentored career development. It is expected that during this time, the scholars will develop a solid portfolio of pilot and preliminary data suitable for competitive extramural grant applications; a robust record of publications and presentations at national scientific meetings; and a program of courses and experiential learning in areas that will advance the scholar’s proficiency in independent translational research. Scholars must demonstrate a productive relationship with qualified and funded mentors who are experienced in advancing the careers of translational researchers. Awardees will recieve up to salary support for 75% up to $75,000 (benefits support up to $25,000).  The scholars will also revcive $25,000 of research expenses, $2,000 travle costs, and $10,000 for support of the mentors lab. 


Scholar Candidates
Scholars supported under the KL2 component must have a research or health-professional doctoral degree or its equivalent.

Scholar appointments
Candidates must have a full-time appointment at UCI.

Selection restrictions
At the time of their appointments, scholars must not have pending an application for any other PHS mentored career development award (e.g. K07, K08, K22, K23) that duplicates any of the provisions of the K component. Former or current PDs/PIs on any NIH research project grant [this does not include NIH small grants (R03), exploratory Developmental (R21) or SBIR, STTR (R43, R44 grants)] or equivalent non-PHS peer reviewed grants that are over $100,000 direct costs per year, or project leaders on sub-projects of program project (P01) or center grants (P50) are NOT eligible to participate as scholars. Appointed scholars are encouraged to apply for individual mentored K awards (e.g. K07, K08, K22, K23) and independent awards (R01, R03, R21); if successful, the KL2 appointment would be terminated and funding received from the new individual K or R award. Scholars to be supported by the institutional career development program must be at the career level for which the planned program is intended.  In keeping with the type of mentoring and career development being provided by the CTSA, a KL2 scholar candidate who is already in the process of applying for an independent mentored career development grant, a P01 grant, or R01 grant is likely too senior for the KL2 award.

The ICTS annually funds three KL-2 scholars. A minimum of 75% effort must be dedicated to pursuing multidisciplinary clinical research and translational science including training and mentoring for a minimum of 2 years. During the 2 years of ICTS support, ICTS will work with the scholar through dedicated mentoring and monitoring to apply for an individual NIH K-award. The faculty scholar's home department, School, or organized research unit is expected to contribute the balance of the scholar's salary and research support during the period covered by the award.

Program Requirements

All KL2 recipients will become part of the ICTS  KL-2 Scholars Program. The specific requirements of the KL2 award, as well as the general requirements of the K Scholars Program, are detailed below:

  • Professional Effort Devoted to the Program and Source of Funding
    Generally, 75% of a Scholar's full-time professional effort must be devoted to the KL2 award for the training and clinical research activities. The 75% effort is based on the entire amount of time worked in a typical week, and should include proportionate amounts of normal weekday time. The remaining 25% effort can be divided among other clinical, administrative, and teaching activities that are consistent with the proposed goals of the KL2 award.

Sources of support for the 75% KL2 effort include the ICTS KL2 grant for amounts up to $100,000 per year (including benefits), and the department of the KL2 scholar for any remaining gap between $100,000 and 75% of the salary of the scholar (i.e., the salary gap), as well as the remaining 25% of the scholar's salary. NIH rules prohibit KL2 scholars from receiving salary support from other federal grants and contracts (except in the final two years of K funding, as noted below); however, other intramural and non-federal extramural grant sources may be used for this purpose. Scholars who acquire non-federal sources of funds that are appropriate for this use, such as foundation career development grants, may reasonably be expected by their department to allocate part of the award to help cover their salary gaps.

  • Didactic Training in Clinical and Translational Research
    Training in a comprehensive clinical research program is imperative for establishing independence as a clinical investigator and a secondary degree in a clinical research-related field is an important attribute.

The training requirement will normally be met through FFAST didactic programs.

  • Mentors
    Developing a successful clinical research career requires strong relationships with mentors and a research team. Each Scholar must have a lead mentor and at least one other mentor from a different discipline. Mentors should have sufficient independent research support to cover the costs of the proposed research project that exceed the scholar research funds provided by the KL2.

Lead mentors will have overall responsibility for helping Scholars develop creative and independent careers in research. In addition to being an expert in the scientific area the Scholar has chosen to pursue, a lead mentor must be familiar with faculty, resources and databases at UCI, and have resources and research staff that can support the Scholar's research. Lead mentors will provide guidance to assure that projects are moving satisfactorily on the path to presentations, publications, and grant applications, and they will provide advice about career directions, national networking, and academic promotion. They will also help to assure that 75% of the Scholar's total work week is protected from clinical and administrative duties, and fully available for training and research. Co-mentors will be responsible for working with the lead mentor on these responsibilities, and will provide guidance in one or more complementary areas of expertise.

Scholars will meet frequently with the lead mentor. Scholars will also meet regularly with their co-mentors, and at least twice a year with all their mentors as a group. Mentors are encouraged to participate in the Scholar's Progress meeting each year, and to work with the scholar on a Career Development Plan. Each scholar is also expected to meet periodically with her/his division head/department chair who will oversee the scholar's departmental interactions and academic advancement.

  • Key Program Elements
    • Scholar career development plans, progress reports, and performance feedback

Scholar Milestones

Since our shared goal is for scholars to become independently funded by the end of their K award period (or earlier), we set out these general guidelines for scholars to consider:

By the end of the 2nd year, and each year thereafter:

      • 3 peer-reviewed publications submitted, two of these as first or last author and two representing original research.
      • One multidisciplinary extramural grant of any size submitted (typically R21, R03, or other federal, state, foundation, industry, or intramural grant).
      • In addition, KL2 Scholars are strongly encouraged to submit an individual K award application (K23, etc.) that will replace the KL2, extend funding through six years, and offer the advantages of being a PI on a grant from the NIH institute of choice.

By the end of the 3rd Year 

      • One multidisciplinary, R01 grant (or equivalent) submitted.
    • Scholar Performance Reviews

Six month

        • Scholars will submit a 6 month progress report and meet with the K Program staff to review their progress on their research progress and IDP.

Application Process

  • The final application includes:
    • Scholar Information. (4 Pages) Please address:
      • Summary of the degree to which the application meets five ICTS-KL-2 scholar selection criteria
        • Format.  Substantial face-to-face discussions among the career recipient/scholars, other individuals in a similar training status, and mentors along with a combination of didactic and small-group discussions (e.g. case studies) are highly encouraged.
        • Subject Matter. While there are no specific curricular requirements for instruction in responsible conduct of research, the following topics have been incorporated into most acceptable plans for such instruction:
          • conflict of interest – personal, professional, and financial
          • policies regarding human subjects, live vertebrate animal subjects in research, and safe laboratory practices
          • mentor/mentee responsibilities and relationships
          • collaborative research including collaborations with industry
          • peer review
          • data acquisition and laboratory tools; management, sharing and ownership
          • research misconduct and policies for handling misconduct
          • responsible authorship and publication
          • the scientist as a responsible member of society, contemporary ethical issues in biomedical research, and the environmental and societal impacts of scientific research
        • Faculty Participation. Mentors and other appropriate faculty are highly encouraged to contribute both to formal and informal instruction in responsible conduct of research. Informal instruction occurs in the course of laboratory interactions and in other informal situations throughout the year.
        • Duration of Instruction. Instruction should involve substantive contact hours between the career recipient/scholars, mentors and other appropriate faculty. Acceptable programs generally involve at least eight contact hours. A semester-long series of seminars/programs may be more effective than a single seminar or one-day workshop because it is expected that topics will then be considered in sufficient depth, learning will be better consolidated, and the subject matter will be synthesized within a broader conceptual framework.
        • Frequency of Instruction. Reflection on responsible conduct of research should recur throughout a scientist's career. Individual scholars are strongly encouraged to consider how to optimize instruction in responsible conduct of research for the particular career stage(s). Instruction must be undertaken at least once during each career stage, and at a frequency of no less than once every four years. Individuals at the early career investigator must receive instruction in responsible conduct of research at least once during this career stage.
    • Statement of research interests and career goals (limit to 1000 words)
    • Two mentor Support Letters
      • Outline the qualification of the applicant and the availability of resources for the applicant to complete their research
      • Additionally, mentors need to provide a statement regarding their role in career development of the ICTS-KL2 scholar. It should be stressed that primary review criteria include the extent of support provided by the mentor/department and the quality of mentoring.
    • A signed statement of support from the department chair or division chief.
      • This letter need only speak to the availability of resources for the applicant to perform research
    • NIH Biosketch (new format)
    • UCI Financial Disclosure (Form 800 and if requiered Form 810)


Notes and Deadlines

All application documents must be submitted online at www.icts.uci.edu/grants

All general questions should be directed to Diana Vigil dvigil1@uci.edu; (949)824-1231.

This award will follow all NIH Policies. The NIH Polices on K-awards can be found athttp://grants.nih.gov/grants/policy/nihgps_2012/nihgps_ch12.htm


TL-1 Pre and Post Doctoral Scholars Training Award Infromation »

ICTS Pre- and Post-Doctoral TL-1 NRSA Training Program in
Translational Biomedical Research

We are currently accepting applications for 1 Post-doctoral position

Apply Here


The UC Irvine Institute for Clinical and Translational Science NRSA trainee program is funded by the National Institutes of Health National Center for Advancing Translational Science (NCATS) program designed to integrate training in clinical research and translational science into the core curriculum of pre- and postdoctoral trainees in medicine, public health, nursing, pharmaceutical sciences, biomedical and social sciences, physical sciences, engineering, and informatics. 
Duration of support is 1 years with the possibility of a one to two year(s) extension.


Translation: The process of turning observations in the laboratory, clinic and community into interventions that improve the health of individuals and the public - from diagnostics and therapeutics to medical procedures and behavioral changes.

Translational Science: The field of investigation focused on understanding the scientific and operational principles underlying each step of the translational process.

Translational Science Spectrum: The translational science spectrum represents each stage of research along the path from the biological basis of health and disease to interventions that improve the health of individuals and the public. The spectrum is not linear or unidirectional; each stage builds upon and informs the others. At all stages of the spectrum, NCATS develops new approaches, demonstrates their usefulness and disseminates the findings. Patient involvement is a critical feature of all stages in translation.


Each Trainee will receive:

  • Predoctoral
    • Tuition/Fees: 60% of posted UCI graduate tuition/fees up to $8,000 per year
    • Predoctoral Stipend: $22,920 per year
    • Training-related expenses and health insurance up to $4200
    • Travel support: $1,500
  • Postdoctoral
    • Non-degree seeking Trainees: up to $3,000; costs related to seminar registration and formal coursework
    • Degree seeking Trainees: 60% of posted UCI graduate/tuition fees for the MPH or MS-BATS program up to $8,000 per year
    • Training-related expenses: health insurance and research-related expenses up to $7,850
    • Postdoctoral Stipend: dependent on career level 
    • Travel support: $1,500

We are pleased to invite applications for postdoctoral positions. This call is intended to fund 1 Scholar. The appointment must begin by March 31, 2017.

The Applicants Must:

  • Project focused on Translational Research
  • Have 2 Mentors
  • Currently hold a postdoctoral or fellowship position at UCI
  • Be a US Citizen or Green Card Holder

To apply for the ICTS TL-1 Scholar position applicants must submit the following:

  1. Personal Statement describing why you want to do research (Limit to 1,000 words)
  2. NIH BioSketch (new format)
  3. Research Plan Title (Limit 300 characters, including spaces)
  4. Research Plan Summary (Limit 200 words)
  5. Description of multidisciplinary integration of project and/or mentoring team (Limit 50 words)
  6. Research Plan (Limit 3,000 words) consisting of three sections:
    • Description of Research Question
      • Hypothesis and specific aims 
    • Background and Key Literature
    • Study Design/Research Plan (work closely with mentor to write)
    • Bibliography (Not included in the word count)
  7. 2 completed Letters of Endorsement from your Primary Mentor and Co-mentor, including the mentor’s NIH-style Bio-sketch (new format).
  8. Letters of recommendations from at least two faculty members who are familiar with the applicant’s credentials and work. NIH Biographies of the referees are also required. (To be submitted by the referee)
  9. Transcripts (professional school transcripts only, not undergraduate transcripts) (where appropriate; pre-doctoral and doctoral students)

Applications are due on Wednesday, February 8rd by 5PM.

All application documents must be submitted online at www.icts.uci.edu/grants.

Questions should be directed to Diana Vigil dvigil1@uci.edu; 949-824-1231.

Applicants will be notified of the outcome on or before March 10, 2017.


Current KL-2 Scholars

Current TL-1 Trainees


Previously Funded KL-2 Scholars

Previously Funded TL-1 Trainees